03/10/10- News Wire
Advaxis, Inc., the live, attenuated Listeria monocytogenes (Listeria) immunotherapy company has developing a long-term, room temperature, storage-stable form of its vaccines. This would replace the current requirement to keep the product frozen at -70o C before use.
Advaxis has been investigating other methods for preserving its live vaccines without the need for freezing. Although live Listeria can be freeze dried, this method is associated with a loss of 90% or more of the bacterial activity. A recent test of a different method, called “foam drying” has delivered a product, which is stable at room temperature. Recovery of almost 100% of the product was observed and excellent biological activity was seen.
“This exciting work can make it possible to distribute our products to every physician’s office without special equipment using a low cost process,” commented Advaxis Chairman/CEO Thomas A. Moore. “It will be key to the licensing and commercialization of all our vaccine technologies.”